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A Deterministic Model Predicts the Properties of Stochastic Calcium Oscillations in Airway Smooth Muscle Cells

Figure 4

More detailed comparisons between the 2-state and the 6-state models, and a comparison to experimental data.

As a function of concentration (), the two models give the same ISI (A), peak (C) and spike duration (E). These results agree qualitatively with experimental data, as shown in panels B, D and F respectively. Quantitative comparisons are generally not possible as the relationship between concentration and agonist concentration is not known. Error bars represent . Data for each MCh concentration are obtained from at least three different cells from at least two different lung slices.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1003783.g004