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A Deterministic Model Predicts the Properties of Stochastic Calcium Oscillations in Airway Smooth Muscle Cells

Figure 3

A 2-state open/closed model quantitatively reproduces the 6-state model.

A: histograms of interspike interval (ISI) distribution for both the 6-state and the simplified models. The ISI is defined to be the waiting time between successive spikes. Each histogram contain an equal number of samples (180). B: comparison of average ISI, average peak value of ( in the model) and average spike duration. All distributions were computed at a constant .

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1003783.g003