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A Hepatitis C Virus Infection Model with Time-Varying Drug Effectiveness: Solution and Analysis

Figure 6

Approximation to viral dynamics compared to exact dynamics under mericitabine treatment, 750 mg qd, .

(a) For patient 92102 from [16], characterized as “flat”. (b) For patient 92103 from [16], characterized as “non-flat”. (c) Different exponential terms in approximate solution (16) compared with the exact solution for patient 92103, characterized as “non-flat”. Parameter estimates from [16]: For patient 92102, , , , , , , and ; for patient 92103, , , , , , , and .

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1003769.g006