Communication Routes in ARID Domains between Distal Residues in Helix 5 and the DNA-Binding Loops

doi:10.1371/journal.pcbi.1003744

Communication Routes in ARID Domains between Distal Residues in Helix 5 and the DNA-Binding Loops

Figure 8

Paths of long-range communication mediated by Y119 in wt and Y119A ARID3A.

The shortest paths of communications mediated by Y119 in ARID3A_FREE (left panel) and ARID3A_Y119A (right panel) simulations as identified by the PSN-LMI approach are shown as cylinders of thickness proportional to the probability of occurrence. The Y119 Cα and the L64 Cα are also indicated by orange and yellow spheres, respectively. L1 and L2 are highlighted in yellow.

doi: https://doi.org/10.1371/journal.pcbi.1003744.g008