Communication Routes in ARID Domains between Distal Residues in Helix 5 and the DNA-Binding Loops
Figure 6
Shortest paths of long-range communication in ARID3A and Dri.
The edges which are present with highest probability in the paths of long-range communication identified by PSN-LMI approach are indicated for ARID3AFREE (blue) and DriFREE (dark green) simulations by lines of thickness proportional to the occurrence probability. The residues connected by the edges are indicated as spheres, whereas the residues known to compromise the DNA-binding capabilities in ARID3A, along with Q111/Q101 and R109/R99 are shown as sticks if identified in the graph.