Communication Routes in ARID Domains between Distal Residues in Helix 5 and the DNA-Binding Loops
Figure 2
Comparison of LMI matrices describing correlated motions.
The Frobenius norms between average LMI matrices calculated from different replicates of the same target protein are reported. An average LMI matrix achieved from an unfolding simulation at 500K of the same protein is used as a control. The example of DriFREE simulations is reported for sake of clarity. Similar results with even lower Frobenius norms were obtained for ARID3AFREE replicates (average Frobenius norm of 5). Average LMI were calculated with five-ns time-windows, as explained in Materials and Methods. The box on the bottom shows the values of Frobenius when the two halves of each replicate are compared to use as a baseline in the comparison.