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Resolving Anatomical and Functional Structure in Human Brain Organization: Identifying Mesoscale Organization in Weighted Network Representations

Figure 9

Weighted connection matrices for the synthetic benchmark networks and an empirical brain DSI network (N = 1000 nodes).

Because network topologies can be difficult to decipher in large networks, here we illustrate the connections between only 100 of the total 1000 nodes. In each network, the topology changes as a function of edge weight (i.e., color) in the adjacency matrix. The windowed thresholding technique isolates topological characteristics in the subnetworks of nodes of similar weight. We report the initial benchmark results for a window size of 25% but find that results from other window sizes are qualitatively similar (see the Supporting Information).

Figure 9

doi: https://doi.org/10.1371/journal.pcbi.1003712.g009