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Regulation of the Nucleosome Repeat Length In Vivo by the DNA Sequence, Protein Concentrations and Long-Range Interactions

Figure 6

The NRL in mouse pericentric heterochromatin is not determined by the sequence of the major satellite repeats.

A) Regular nucleosome positioning around tandems of repeating 234-bp major satellite repeats predicted from the DNA sequence. B) Frequency of the left and right ends of nucleosomal DNA fragments obtained with paired-end MNase-seq [28]. C) Autocorrelation of the nucleosome start site positions from Panel B reveals a 10-bp periodicity. D) Frequency of the left and right ends of MNase-seq nucleosomal DNA fragments size-selected in the interval [145 bp; 150 bp].

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.1003698.g006