Locating the Route of Entry and Binding Sites of Benzocaine and Phenytoin in a Bacterial Voltage Gated Sodium Channel
Figure 2
Free energy surfaces for (A,C) benzocaine and (B,D) phenytoin in the NavAb central cavity viewed along the pore axis (A,C) and from the membrane (B,D) obtained from metadynamics simulations.
Contours are shown at 1/mol intervals.