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Computational Modeling of Allosteric Regulation in the Hsp90 Chaperones: A Statistical Ensemble Analysis of Protein Structure Networks and Allosteric Communications

Figure 9

The Degree Distribution of Residue Hubs in the Hsp90 Structures.

The number of hub nodes as a function of the degree of a hub is shown for the solution HtpG structure (in blue); the apo-HtpG structure (in red); the ADP-HtpG structure (in green); the ADP-Grp94 structure (in maroon); the ATP-Grp94 structure (in orange); and the yeast ATP-Hsp90 structure (in brown). The coloring annotation of the distribution is consistent with the annotation of residue hubs in Figure 7.

Figure 9

doi: https://doi.org/10.1371/journal.pcbi.1003679.g009