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Comparison of REST Cistromes across Human Cell Types Reveals Common and Context-Specific Functions

Figure 4

Colocalization of REST and its cofactors and their relationship with gene expression.

(A) Venn diagram of colocalization of SIN3, COREST, and EZH2 at REST peaks. The square constitutes all REST peaks. (B) Context enrichment of REST peaks bound by different cofactors; fold enrichment is compared to all REST peaks. (C) Expression of REST targets with different cofactors, plotted as log2(FPKM+0.1); asterisks mark significant differences. Data shown here are for GM12878 and data for Hep G2 are in Figure S6.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1003671.g004