Comparison of REST Cistromes across Human Cell Types Reveals Common and Context-Specific Functions
Figure 3
Transcription of REST targets bound by REST in different contexts.
(A) Comparison of the expression of REST-bound targets (b) vs. unbound REST candidate genes (ubrc; bound in other cell types except the subject one) or all genes (all). (B–D) Expression differences of REST targets: (B) with one peak vs. more peaks; (C) bound by peaks with cRE1, ncRE1, half-site or no RE1; (D) associated to common, shared, or cell-specific peaks. Asterisks mark significant differences in expression (p<0.05). Numbers in boxes are the number of genes whose peak has the specified context. Data plotted as log2(FPKM+0.1) and shown here for T cells, GM12878 cells, neurons and Hep G2 cells; data for other cells are in Table S6.