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Combined Role of Seizure-Induced Dendritic Morphology Alterations and Spine Loss in Newborn Granule Cells with Mossy Fiber Sprouting on the Hyperexcitability of a Computer Model of the Dentate Gyrus

Figure 2

Schematic representation of the strategies used to classify the dendrites and place the synapses.

A. Classification of a dendrite as proximal (PD), medial (MD) and distal (DP) based on the distance from soma up to the branching point of the dendrite (yellow line). B. Location of the synapses depending on the sublayer in which a dendrite section is located.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1003601.g002