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Sensing Membrane Stresses by Protein Insertions

Figure 5

Insertion binding as a function of the initial membrane curvature for the three scenarios of stress generation accompanied by creation of membrane curvature.

The monolayers are laterally uncoupled. The elastic binding energy (A) and the relative binding constant (B) are presented as functions of the membrane curvature before insertion J. (C) The elastic binding energy as a function of the membrane curvature J for insertions of different cross-sectional radii ( in blue, and in black) embedded to the depth . (D) The elastic binding energy as a function of the membrane curvature J for insertions of the cross-sectional radius embedded to three different depths ( in blue, in black, and in red). (E–F) The curvature sensitivity as a function of the insertion radius r (E) and the insertion embedding depth d (F).

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1003556.g005