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Bistable Dynamics Underlying Excitability of Ion Homeostasis in Neuron Models

Figure 5

Bifurcation diagrams of fixed points for different models.

The effects of chloride and active ion channels are compared for each of the four possible pump (A vs B) and current model (Nernst vs GHK) combinations. The physiological equilibrium for normal pump rates ( and ) is marked by a green square. The model from fig. 2 is marked by a star. The value is the same with and without chloride or active channels. Insets show the bifurcation diagrams for low pump rates ( ). Fixed point lines for models without active ion channels are shaded (see insets). Note the different scales on the main figures, insets are for the same range in each panel.

doi: https://doi.org/10.1371/journal.pcbi.1003551.g005