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An In-Silico Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway

Figure 12

Simulation of ABCA1 up-regulation on a virtual population with low HDL-C (≤40 mg/dL).

Each virtual patient seleted for the treatment simulation had its ABCA1 activity () increased by 100% of its initial value.

doi: https://doi.org/10.1371/journal.pcbi.1003509.g012