An In-Silico Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway
Figure 4
The fit of the model to the calibration data: FCR of ApoA-I versus HDL-C/ApoA-I ratio.
The data sources are: Brinton et al [43], Ikewaki et al [45], Schaefer et al [44]. The piecewise linear fit and the confidence interval are discussed in the Methods section. The model simulation values are indicated by asterisk symbols, for the nominal subject and the heterozygote, homozygote of CETP mutation.