Spatio-Temporal Simulation of First Pass Drug Perfusion in the Liver
Figure 3
From in vivo scans to vascular geometry.
Based on an in vivo micro-CT scan (a) of a mouse, vascular structures (b) in the liver are segmented and skeletonized. The supplying and draining vascular systems (SVS and DVS) are shown in red and blue, respectively. Furthermore, the liver is segmented and decomposed in lobes shown in different colors in (c). An algorithmic procedure is used to determine physiological vascular structures (d) with the desired level of detail, in our case leaf nodes (end points) for each of the two trees are used.