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Structural Insights into E. coli Porphobilinogen Deaminase during Synthesis and Exit of 1-Hydroxymethylbilane

Figure 12

Protein relaxation after product exit.

A. Probability distribution graph of radius of gyration of the protein in DPM, P6M and no-HMB stages showing that in the no-HMB stage, the Rgyr falls back close to the DPM stage. DCCM plots of B. no-HMB; C. DPM; and D. P6M stages, showing the differences and similarities in correlation to the DPM stage as the protein relaxes from no-HMB stage. The marked regions in the no-HMB stage resemble more to DPM stage during protein relaxation.

Figure 12

doi: https://doi.org/10.1371/journal.pcbi.1003484.g012