In Silico Single-Molecule Manipulation of DNA with Rigid Body Dynamics
Figure 3
Comparison to force-extension curves.
Red circles: dimensionless stretching force as a function of the mean relative extension
. Here the radius of the cylinders is
corresponding to the
mmol monovalent salt buffer used in [1]. The other parameters of the simulation are given in Table 1. For comparison, the black solid line reproduces the analytical Worm-Like-Chain force-extension approximation formula [35]. Black triangles correspond to a numerical fit of the exact Worm-Like-Chain model [34] with the same persistence length
. Blue crosses: we also show simulations in the limit case
, with no torsional rigidity (
) and no collisions, and compare it to the theoretical force-extension curve of a Freely-Jointed-Chain (FJC, blue solid line). The statistical error bars on the simulation points are all smaller than the symbol size.