Correlation between Oncogenic Mutations and Parameter Sensitivity of the Apoptosis Pathway Model
Figure 6
Comparison of parameters linked to sensitivity of caspase3 levels and gene mutations.
The numbers in the frame indicate the number of occurrences in the mutation spectrum of the gene relating to the corresponding parameters. Magenta bar, change in the steady-state concentration of caspase3; Green bar, change in the critical point of bifurcation. gpre-casp, the basal generation rate of pre-caspase; dcaspase, the degradation rate of caspase3.