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Correlation between Oncogenic Mutations and Parameter Sensitivity of the Apoptosis Pathway Model

Figure 4

Parameter sensitivity analysis.

(A) The change of the saddle-node bifurcation point in response to a 20% increase or decrease in each parameter of the apoptosis pathway. (B) The change in the steady-state concentration of caspase3 in response to a 20% increase or decrease in each parameter of the apoptosis pathway.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1003451.g004