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An Allosteric Signaling Pathway of Human 3-Phosphoglycerate Kinase from Force Distribution Analysis

Figure 2

Forces exerted by the ligands on the protein.

Absolute value of the averaged residue-wise forces between (A) BPG and hPGK residues, (B) ADP and hPGK residues. Experimentally identified binding residues are marked with vertical lines and labels for BPG (A) and ADP (B), respectively.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1003444.g002