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PEX5 and Ubiquitin Dynamics on Mammalian Peroxisome Membranes
Figure 5
Ubiquitin thresholds for cooperative coupling.
(A) Example time dependence of total peroxisomal ubiquitin for cargo addition rate 
, with the default number of peroxisomes (
) and importomers per peroxisome (
). The characteristic timescale for fluctuations in the ubiquitination level is several seconds. Two possible threshold values are illustrated with dashed lines. (B) The average interval of time spent below a given threshold vs. 
for thresholds as indicated by the legend, which also applies to (C). (C) The average interval of time spent above a given threshold vs. 
.
doi: https://doi.org/10.1371/journal.pcbi.1003426.g005