< Back to Article

Electrodiffusive Model for Astrocytic and Neuronal Ion Concentration Dynamics

Figure 8

Model comparison.

(A) Six model versions, three spatially extended models (solid lines), and three point models (dashed lines). Two versions (black lines) included an active astrocyte. In two versions (red lines), the astrocyte volume had been exchanged with an enhanced ECS (the total ECS volume fraction increased to ). In two versions (blue lines), the original ECS volume fraction () was kept when the astrocyte was removed. (B) The performance of the six model versions were compared in terms of maximal in the input zone during a constant K⁺ influx to the system. (C) To compare the time course of the dynamics, the responses (in B) were normalized to the peak amplitude for each respective trace.

doi: https://doi.org/10.1371/journal.pcbi.1003386.g008