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Electrodiffusive Model for Astrocytic and Neuronal Ion Concentration Dynamics

Figure 2

Summary of the two-domain electrodiffusive formalism.

The set of equations summarizes the electrodiffusive formalism. In equations containing the symbol “±”,“+” should be used for intracellular domain () and “−” should be used for the extracellular domain (). The formalism is general to the choice of membrane mechanisms. , representing system specific membrane mechanisms (ion pumps, ion channels, cotransporters ect.), must to be specified by the user. External input to the system must also be specified. The input must be locally electroneutral, i.e., must fulfill .

doi: https://doi.org/10.1371/journal.pcbi.1003386.g002