Amino Acid Changes in Disease-Associated Variants Differ Radically from Variants Observed in the 1000 Genomes Project Dataset
Figure 11
Amino acid mutability rank order plot comparing the mutability scores for 1 kG, OMIM and Humsavar residues.
The most mutable amino acids are at the top. Correlation coefficients for 1 kG vs OMIM, 1 kG vs Humsavar and OMIM vs Humsavar are 0.09, 0.17 and 0.51, respectively.