Amino Acid Changes in Disease-Associated Variants Differ Radically from Variants Observed in the 1000 Genomes Project Dataset
Figure 5
Site properties for all residues, 1 kG nsSNPs, OMIM nsSNPs and Humsavar nsSNPs in the structure 3D set.
(A) the solvent accessibility for the variants in the four datasets, (B) the secondary structure in which each of the variants occurs, (C) the functional annotation of every variant in the four datasets.