Multiscale Modeling of Influenza A Virus Infection Supports the Development of Direct-Acting Antivirals
Figure 3
Model predictions reproduce data for different infection conditions.
The model fit from Figure 2 (dashed, □) was used to predict the percentage of uninfected cells (A) and the infectious virus titer (B) for infections at an MOI of 10−4 (solid, ○) and of 3 (dash-dotted, Δ), respectively. These predictions were compared to data sets not used for model construction. Measurements were adopted from Isken et al. and are representative of three independent experiments [35].