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Next-Generation Sequence Assembly: Four Stages of Data Processing and Computational Challenges

Figure 3

Overlap-based approach for graph construction.

(A) Overlap graph where nodes are reads and edges are overlaps between them. (B) Example of a Hamiltonian path that visits each node (dotted circles) exactly once in the graph (note: starting node is chosen randomly). (C) Assembled reads corresponding to nodes that are traversed on the Hamiltonian path.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1003345.g003