Assessing Computational Methods for Transcription Factor Target Gene Identification Based on ChIP-seq Data
Figure 5
Gene density in target regions.
Gene dense regions tend to contain more binding events (peaks) than gene sparse regions of the genome. The figure shows gene density (number of genes inside 1 Mb regions around the target gene's TSS) of the regions harboring the top 500 genes across the studies in the (A) HemoChIP and (B) ESChIP datasets.