Structure-Based Function Prediction of Uncharacterized Protein Using Binding Sites Comparison
Figure 4
Tm1631-DNA model based on comparison of Tm1631 protein (1vpq) to known endonuclease IV-DNA complex (2nqj) from PDB.
Tm1631 is white, endonuclease IV is blue, DNA is green and light-blue cartoons, sulfate ions are CPK sticks, crescent-shaped grooves in both proteins are shaded areas. Initial Tm1631-DNA model; Tyr47 and Tyr48 penetrate the DNA's extra-helical region (left). Endonuclease IV-DNA complex (right).