Cell-Based Multi-Parametric Model of Cleft Progression during Submandibular Salivary Gland Branching Morphogenesis
Figure 5
An organ-level simulation containing three ideally localized clefts is shown at (a) 0 MCS and (b) 1500 MCS (Scale = 50 µm). The results were quantified with (c) cleft depth and (d) spanning angle. A slight decrease in the average cleft depth and increase in the average spanning angle was observed relative to the single cleft model run under the same basal conditions.