Prediction of Drug-Target Interactions for Drug Repositioning Only Based on Genomic Expression Similarity
Figure 5
The performance of LOOCV suggests that at mRNA level, the genomic reactions of ligands binding differ dramatically from target to target.
Here all the targets are displayed in several families, according to their functional origins. The height of each bar represents the AUC level (and 95% confidence interval). And the color of each bar indicates the significance level of benchmark ligands enrichment.