Comparing Algorithms That Reconstruct Cell Lineage Trees Utilizing Information on Microsatellite Mutations
Figure 3
Performance of different methods on the same dataset.
Two reconstructed lineage trees containing the same cells from three different mice are shown: M1 (turquoise), M3 (blue), and M4 (orange). (A) A tree using the NJ algorithm along with the Normalized-Absolute distance measure. (B) A tree using the NJ algorithm along with the Equal or Not distance measure. The root of the trees (colored in black) is the weighted mean of the organisms' putative zygotes. It can be seen that the performance of the Normalized-Absolute distance measure is clearly better.