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Reconstructing the Genomic Content of Microbiome Taxa through Shotgun Metagenomic Deconvolution

Figure 5

Reconstructing the genomic content of genera from HMP tongue dorsum samples.

(A) The average similarity in KO content between each reconstructed genus and sequenced genomes from the various genera. Similarity is measured by the Jaccard similarity coefficient, over the set of the 500 KO with the highest variation across samples. Genera are ordered by their mean abundance in the set of samples under study. Entries highlighted with a black border represent the highest similarity in each row. (B) The average similarity between sequenced genomes from the various genera. Similarity was measured as in panel A.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1003292.g005