Perturbation Biology: Inferring Signaling Networks in Cellular Systems
Figure 3
BP is significantly faster than Monte Carlo (MC) with comparable accuracy.
(A) BP converges three orders of magnitude faster than MC, even as the size of the system increases to 100 nodes. In this test, the number of training patterns equals the number of nodes in both BP and MC. (B) The means of the distributions from BP are plotted against the true non-zero parameters from the set of the data generators. BP has a high correlation (R = 0.7) with the true parameter values, with many points exactly on the diagonal. (C) MC and BP produce low errors per data point compared to random interaction assignments (Red bar).