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Catalysis of Protein Folding by Chaperones Accelerates Evolutionary Dynamics in Adapting Cell Populations

Figure 3

The time evolution of mean protein stabilities and mean interaction probabilities of functional dimers in the absence and presence of chaperones, i.e. for (blue lines) and (red lines), respectively, at temperature T = 0.85.

(A) The time evolution of stability for monomeric proteins. (B) The time evolution of mean stability, for heterodimer proteins. (C) The time evolution of mean stability, for date triangle proteins. (D) The time evolution of interaction probability, for the heterodimer complexes. (E) The time evolution of mean interaction probability, for the date triangle complexes.

Figure 3

doi: https://doi.org/10.1371/journal.pcbi.1003269.g003