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A Simple Rule for Dendritic Spine and Axonal Bouton Formation Can Account for Cortical Reorganization after Focal Retinal Lesions

Figure 12

Electrical activity in terms of total number of firing neurons (excitatory and inhibitory) in time bins of measured in the peri-LPZ and LPZ before and after the lesion.

A) Physiological case of network reorganization, with and . B) Aberrant case of network reorganization with and . Before the lesion, the networks show irregular activity (left column). In the early phase after the lesion (middle column), the number of firing neurons is strongly reduced. In the late phase after the lesion (right column), the network either returns to a state of irregular activity (A), or turns into a state of more synchronized activity, with strong oscillations in electrical activity (B).

Figure 12

doi: https://doi.org/10.1371/journal.pcbi.1003259.g012