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Predictive Modeling of In Vivo Response to Gemcitabine in Pancreatic Cancer

Figure 4

Measurement of tumor radii from bioluminescent imaging of untreated and gemcitabine-treated SCID mice.

Gompertz growth curves were fitted to these data to illustrate the tumor growth. (A) MiaPaCa-2 radii and fitting to Gompertz equations (untreated) and (treated). (B) Bioluminescence signal shown for representative mice with S2-VP20 tumors. (C) S2-VP10 radii and fitting to Gompertz equations (untreated) and (treated). (D) Bioluminescence signal shown for representative mice with S2-VP20 tumors. Error bars in (A) and (C) correspond to standard error of the mean.

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.1003231.g004