Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model
Figure 2
Inward current-voltage rectification for ChR2 in experiments (left) and in the model (right).
Experimental (A) and model (B) example traces for ChR2 current in response to 0.5 s light pulses, 470 nm, at specified irradiances and holding voltages. CD. Current-voltage (I–V) curves for the peak current (IP). EF. Current-voltage (I–V) curves for the steady-state current (ISS). GH. Ratio of ISS/IP as a function of voltage. Experimental data in C, E, and G are presented as mean±S.E., n = 7.