The Next Generation of Transcription Factor Binding Site Prediction
Figure 7
ROC curve analysis of STAT4 and STAT6 ChIP-seq data.
TFFMs allowing a flexible length motif have been compared to PWMs, DWMs, GLAM2, and fixed-length TFFMs on STAT4 (A) and STAT6 (B) ChIP-seq data. Flexible TFFMs do not significantly perform better than fixed-length TFFMs. DWMs, PWMs, and GLAM2 produce a lower discriminative power than the TFFMs.