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Mammalian Rest/Activity Patterns Explained by Physiologically Based Modeling

Figure 5

Experiments and simulations of temporal niche switching in degus.

Temporal niche switching can be elicited in degus by the presence of a running wheel (days 1–22 and 68–108) in either LD (30 lux from clock time 8–20; days 1–88) or DD conditions (days 89-end). Panel (A) shows data from a single animal, with dark bars representing periods of above average core body temperature. Panels (B)–(D) show raster plots for single runs of the model using the same protocol, with dark bars representing periods of high activity ( s−1), averaged in 10 min sliding windows. All raster plots are double-plotted. The effect of the running wheel is modeled by: (B) masking and circadian signal inversions, (C) circadian signal inversion, and (D) masking inversion. The data in panel (A) are adapted from [9] and manually replotted here.

Figure 5

doi: https://doi.org/10.1371/journal.pcbi.1003213.g005