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Structural Similarities and Differences between Amyloidogenic and Non-Amyloidogenic Islet Amyloid Polypeptide (IAPP) Sequences and Implications for the Dual Physiological and Pathological Activities of These Peptides

Figure 6

Root mean square fluctuation (RMSF) of each residue (Cα atom) of the four IAPP variants in the super structural families at 300 K.

Residues 1–17 were aligned preceding the RMSF calculations.

doi: https://doi.org/10.1371/journal.pcbi.1003211.g006