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Structural Similarities and Differences between Amyloidogenic and Non-Amyloidogenic Islet Amyloid Polypeptide (IAPP) Sequences and Implications for the Dual Physiological and Pathological Activities of These Peptides

Figure 3

Secondary structure propensities of the four IAPP variants at 300 K.

Stardard deviation was calculated from the last 3 blocks of the simulation data (100 ns of each) at 300 K.

doi: https://doi.org/10.1371/journal.pcbi.1003211.g003