How MicroRNA and Transcription Factor Co-regulatory Networks Affect Osteosarcoma Cell Proliferation
Figure 5
miR-9-5p and SP1 co-regulatory motifs.
The co-regulatory motifs of miR-9-5p and SP1 are illustrated as graphs with nodes and edges for (A) C1 and (B) C2. MicroRNAs are marked with diamonds, TFs with triangles, primary targets with rectangle, and secondary targets with a circle. Yellow edges tag protein-DNA interactions, blue edges microRNA-target interactions, and dashed edges protein interactions. The red/green color code presents the corresponding log2 FC.