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How MicroRNA and Transcription Factor Co-regulatory Networks Affect Osteosarcoma Cell Proliferation

Figure 2

Clustering of differentially expressed microRNAs.

The heatmap illustrates the expression profiles of DE microRNAs (log2 FC≥|1| & FDR<0.05, y-axis) among all OS cell samples (x-axis). High (dark blue) and low (light blue) proliferative OS samples are clearly separated. The red/green color code corresponds to the expression deviation from the average expression among all samples. Complete-linkage clustering was performed with the Pearson correlation as distance metric.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1003210.g002