On the Importance of Polar Interactions for Complexes Containing Intrinsically Disordered Proteins
Figure 5
Box plots of changes in free energy of binding (ΔΔGbind) in the alanine scan.
Free energy changes for hydrophobic residues, charged residues, and only charged residues that are forming salt bridge interactions are shown in (a), (b) and (c), respectively. Asterisks identify distributions that are significantly different (p values<0.05; Wilcoxon test). The results for residues in the ID segments, ID binding partners (BPs), and 3D complex proteins are shown in red, magenta and grey respectively.