A General Model for Toxin-Antitoxin Module Dynamics Can Explain Persister Cell Formation in E. coli
Figure 2
Numerical simulation of the generic TA model including two independent binding sites.
The systems were simulated for 500 minutes per individual cell. The graphs show the results for a single cell (color-coded towards the species plotted: free antitoxin (green), free toxin (red), AT complex (dark blue), TAT complex (cyan) or free operator DNA (gray)) as well as an average of 1000 cells (in black). The used parameter sets are indicated above the panels. No toxic feedback effects are included: .