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Finding Associations among Histone Modifications Using Sparse Partial Correlation Networks

Figure 2

a) Network in CD4+ cells.

Blue edges represent negative partial correlations, while red edges represent positive partial correlations. b) Overlap with the CD4+ network built on numerical data. Numerical data means that the counts are taken to the log instead of being ranked, so quantitative information is preserved. There is very little difference between the two networks. c) Consensus network. Blue edges represent negative partial correlations, while red edges represent positive partial correlations. Bright edges (blue and red) represent edges that are common to all networks, light edges (light blue and pink) are found in two networks out of three. Any blue means a negative partial correlation, while red or pink means a positive partial correlation.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.1003168.g002